Who we are.

Join the fight against pancreatic cancer! The 2015 Pancreatic Cancer Research Walk is Sunday, November 1st at Sloan's Lake Park, Denver, CO.

All the money raised goes directly to pancreatic cancer research thanks to the Lustgarten Foundation!

Wednesday, February 29, 2012

Resources to help you navigate pancreatic cancer


Understanding Pancreatic Cancer: A Guide for Patients and Caregivers

 The Lustgarten Foundation partnered with leading full-service medical education companyRobert Michael Educational Institute to produce a full-color Guide for individuals with pancreatic cancer and their loved ones.
Understanding Pancreatic Cancer: A Guide for Patients and Caregivers offers the most up-to-date, comprehensive information on the disease. Individual copies of the Guide are available at no cost by request to the Foundation.Call 1-866-789-1000 to request a copy of the Guide.
The Guide can also be downloaded in PDF format. To view PDF files you may need to download a PDF viewer such as Adobe Reader.

Tuesday, February 28, 2012

Costs of cancer care overwhelm patients -- from the Denver Post


Patti Tyree was afraid that cancer would steal her future. Instead, the cost of treating it has.

She had hoped to buy a small farm with money inherited from her mother. But copayments for just one $18,000 round of breast chemotherapy and one shot of a nearly $15,000 blood-boosting drug cost her $2,000.

Bills for other treatments are still coming, and almost half of her $25,000 inheritance is gone.

"I supposedly have pretty good insurance," said Tyree, 57, a recently retired federal worker who lives near Roanoke, Va. "How can anybody afford this?"

Forty years after the National Cancer Act launched the "war on cancer," the battle is not just finding cures and better treatments but also being able to afford them.

New drugs often cost $100,000 or more a year. Patients are being put on them sooner in the course of their illness and for a longer time — sometimes for the rest of  their lives. The latest trend is to use these drugs in combination, guided by genetic tests that allow more personalized treatment but also add to its expense.

It's not just drugs: Radiation treatment is becoming more high-tech, and each leap in technology has brought a quantum leap in expense. Proton therapy is one example — it costs twice as much as conventional radiation and is attracting prostate cancer patients despite a lack of evidence that it is any better.
The financial strain is showing: Some programs that help people pay their bills have seen a rise in requests, and medical bills are a leading cause of bankruptcies.

"Patients have to pay more for their premiums, more for their copayments, more for their deductibles. It's become harder to afford what we have, and what we have is becoming not only more costly but also complex," said Dr. Michael Hassett, a cancer specialist and policy researcher at Dana-Farber Cancer Institute in Boston.

Insurers also are being squeezed by laws that require coverage and restrict raising premiums. And the burden is growing on Medicare, which in some cases is paying for treatments and tests that have not been shown to benefit.

Why have costs escalated so much?

To some extent, it's the price of success.

Survival adds to medical expenses


Cancer deaths have been declining in the United States since the early 1990s. Two out of 3 people now live at least five years after a cancer diagnosis, up from 1 out of 2 in the 1970s, according to the American Society of Clinical Oncology, doctors who treat the disease. Nine out of 10 women with early-stage breast cancer are alive five years after their diagnosis and are probably cured.

Modern treatments have fewer side effects and allow patients to have a greater quality of life than chemotherapy did in the past. But they are far more toxic financially.

Of the nation's 10 most expensive medical conditions, cancer has the highest per-person price. The total cost of treating cancer in the U.S. rose from about $95.5 billion in 2000 to $124.6 billion in 2010, the National Cancer Institute estimates. The true tab is higher — the agency bases estimates on costs from 2001-2006, before many expensive treatments came out.

Cancer costs are projected to reach $158 billion, in 2010 dollars, by the year 2020, because of a growing population of older people who are more likely to develop cancer.

That's the societal cost. For individual patients, costs can vary widely even for the same drug. Dr. Bruce Roth, a cancer specialist at Washington University in St. Louis, tells of Zytiga, a prostate cancer medicine approved last year. It costs $6,100 a month and insurers differ on how much they cover.
"I've had one patient pay $1.50 copay a month and another patient be quoted $5,943," Roth said. Now whenever he hears about a promising new cancer drug, he worries it will be another "where finances end up determining who gets it."

Tyree, the woman from Virginia, said the hospital billed her insurer $14,865 for Neulasta, a shot to boost white blood cells and help her tolerate chemotherapy. Several cancer specialists said Neulasta usually costs less than half that amount, but the charge was $12,000 for Tyree's friend, and blog postings by other cancer patients tell similar stories.

The worst part: A much cheaper alternative is available, but many patients aren't offered that option. There's even a cheaper way to get Neulasta, but hospitals make a lot of money giving the shot instead of teaching a patient or a caregiver how to do that.

Tyree said doctors told her Neulasta was "completely routine and everybody got it." She had no idea how much she and her insurer would have to pay for it until the bill came.

Burden especially hits middle class


A recent American Cancer Society survey found that one-quarter of U.S. cancer patients put off getting a test or treatment because of cost, the group's chief medical officer, Dr. Otis Brawley, writes in his new book "How We Do Harm," which discusses costs and argues for more rational use of health care. One out of 5 survey respondents over 65 said they had used all or much of their savings on cancer care.

The burden hits hard on the middle class — people too well off for programs that cover the poor but unable to afford what care often costs.

Dr. Amy Abernethy, director of the cancer care research program at Duke University, did a study of 250 such patients from around the country. Most were women with breast cancer, including Tyree. All but one had insurance, and two-thirds were covered by Medicare. The vast majority also had prescription drug coverage.
Their out-of-pocket expenses averaged $712 a month for doctor visits, medicines, lost wages and travel to appointments. To pay for cancer drugs, half spent less on food and clothes, and 43 percent borrowed money or used credit. Also, 26 percent did not fill a prescription, 22 percent filled part of one and 20 percent took less than prescribed.

"Patients don't just have cancer, and that's becoming more and more of a problem" because they also are struggling to buy medicines for heart disease, diabetes and other conditions, Abernethy said.

Desperate patients often demand treatments that have a very small chance of helping them. And many doctors feel they have a duty to offer anything that might help, regardless of the cost to insurers and society, said Hassett, the policy researcher from Boston.

How to delve into details of costs


Cancer care is a commodity, and patients are also consumers. They should ask doctors about the cost of their treatments, or get a friend or relative to do it if they are uncomfortable asking pointed questions. Either way, experts say these are reasonable questions, especially because costs can be financially challenging:


• Ask your doctor how much a treatment will cost and whether there are more affordable alternatives. If the recommended treatment is expensive, ask how much better a survival advantage it offers.
• Find out what insurance will and will not cover before agreeing to a treatment. If it's near the end of a year, see if moving up or slightly delaying a treatment makes a big difference in your copayments or deductible.
• Check out programs at hospitals, drug companies and foundations that aid uninsured or underinsured patients. Some are listed in the websites below.

Advice on costs: http://bit.ly/arjDb2
Questions to ask doctors: http://bit.ly/wdzaj3
Financial help: www.needymeds.org and http://bit.ly/nzlqcB
The Associated Press


http://m.denverpost.com/denverpost/db_/contentdetail.htm?contentguid=I8ORaDpF&full=true#display

Monday, February 27, 2012

Managing Side Effects


Need help managing the side effects of cancer treatments?  Here's some suggestions that can help.

The Cancer JourneyA Web site of the Oncology Nursing Society (ONS) designed to help cancer patients and caregivers understand and manage common treatment-related symptoms.


Pain & Fatigue

American Pain Foundation
The Web site of The American Pain Foundation is intended to serve as a resource center for people with pain, their families, friends, and caregivers. Go to Patient Information, then Cancer Pain for in-depth information about the causes of cancer pain and ways to manage it.
American Pain Society
The web site of the American Pain Society enables visitors to search for pain treatment centers nationwide, as well as link to other organizations designed to assist people coping with pain.

Learn more at:

Saturday, February 25, 2012

Caregiver Resources from Lustgarten


Visit Lustgarten's site to learn more:

http://www.lustgarten.org/Page.aspx?pid=643


Managing Practical Concerns

Cancer Survival Toolbox
This self-learn audio program is available free-of-charge from the National Coalition for Cancer Survivorship (NCCS). The program is designed to cover topics or skills that can assist individuals with cancer in meeting the challenges of their illness. It is appropriate for individuals facing any stage of the cancer disease, and includes helpful information for family members or caregivers of cancer patients.
CaringBridgeCaringBridge offers free, private Web sites for people facing a serious health event. Using a CaringBridge Web page, patients and caregivers can share updates, post photos, and receive messages of hope and encouragement through a guestbook.
Family Caregiving 101This site provides caregivers with the basic tools, skills and information they need to protect their own physical and mental health while they provide high quality care for loved ones. The site provides assistance, answers, ideas and helpful advice.
Family Caregiver Alliance
1-800-445-8106
A public voice for caregivers, FCA offers practical tools and information, support services and other resources.
Lotsa Helping HandsLotsa Helping Hands is a private, web-based caregiving coordination service that allows family, friends, neighbors, and colleagues to create a community to assist a family caregiver with the daily tasks that become a challenge during medical crisis, caregiver exhaustion, etc. 

Support & Information 

CancerNet
The consumer Web site of American Society of Clinical Oncology (ASCO), People Living With Cancer is designed to help patients and their families find accurate, timely, and oncologist-approved information about cancer. In addition to providing detailed information, the site includes access to a medical dictionary and drug database, message boards and opportunities to participate in live chats with cancer experts.
Cancer Supportive Care
This comprehensive guide for patients and their families, based on the bookCancer Supportive Care by Ernest H. Rosenbaum, M.D. and Isadora R. Rosenbaum, M.A, is made available on-line from the Cancer Supportive Care Program.
NFCA educates, supports, empowers and speaks up for the more than 65 million Americans who care for loved ones with a chronic illness or disability or the frailties of old age. NFCA reaches across the boundaries of diagnoses, relationships and life stages to help transform family caregivers' lives by removing barriers to health and well-being.
The Well Spouse Association is a nonprofit membership organization that advocates for and addresses the needs of individuals caring for a chronically ill and/or disabled spouse/partner.

Home Care & Hospice

Cancer Support CommunityHelpline: 1-800-658-8898
Multilingual Helpline: 1-877-658-8896
Caring Connections provides free resources and information to help people make decisions about end-of-life care/services before a crisis.
Includes information and resources for identifying home care services for individuals with cancer.
NAHC produces a consumer guide, How to Choose a Home Care Provider: A Consumer's Guide.
Hospice Foundation of America

Hospice Net
Information for patients and caregivers on end-of-life issues and bereavement.
Next Step in Care
Comprehensive information and advice to help family caregivers plan various transitions for patients.

Thursday, February 23, 2012

Looking for a clinical trial? Lustgarten can help!


Clinical Trials

1-800-535-1867
The Lustgarten Foundation, in cooperation with EmergingMed, is pleased to offer a Clinical Trials Matching and Referral Service. The Service provides free and unlimited access to current, verified clinical trial information. A unique and key element of the Service is providing direct and ongoing telephone support throughout the clinical trial search process.


Additional Clinical Trials Search Services

The National Institutes of Health (NIH) Cancer Trials
The cancerTrials area of the National Institutes of Health (NIH) will help you understand clinical trials and the process of informed consent, as well as provide a list of studies.
Cancer Trials Support Unit (CTSU)
The Cancer Trials Support Unit (CTSU) is an NCI-funded program to facilitate participation by patients and physicians in Phase III NCI-sponsored cancer treatment trials. 
TrialCheck (Coalition of Cancer Cooperative Groups)
TrialCheck is a user-friendly cancer clinical trial search engine created by the Coalition of Cancer Cooperative Groups.

Wednesday, February 22, 2012

Upcoming Opportunities to Fight Pancreatic Cancer in Colorado!



DENVER

2/23 PurpleStride Denver Planning Meeting
Help us make our inaugural PurpleStride a success!

3/1 Denver Volunteer Meeting
Join the fight against pancreatic cancer!

6/24 PurpleStride Denver
Register today!

Contact us about volunteering in Denver!

COLORADO SPRINGS/PUEBLO

Volunteer in Colorado Springs/Pueblo!

Rare mutations tied to breast, pancreatic cancers: study


  • By Genevra Pittman
NEW YORK | Wed Feb 15, 2012 2:28pm EST


(Reuters Health) - Mutations in genes that fix mismatched DNA may put people at extra risk for breast cancer and pancreatic cancer, in addition to their well-known ties to colon and endometrial cancers, a new report suggests.

But close relatives of people with the inherited mutations, known collectively as Lynch syndrome, don't seem to have any extra cancer risk if they test negative for the defective genes, researchers reported Monday in the Journal of Clinical Oncology.

The mutations "are very rare," according to Mark Jenkins, from the University of Melbourne. Researchers don't know exactly how common Lynch syndrome is, in part because people aren't generally tested unless they have a family history of colon or endometrial cancer.

Jenkins, who worked on the study, said that at most one in 1,000 people probably has the condition.
Still, "the consequences for them are quite severe because the risks of cancer for them are quite high," Jenkins told Reuters Health.

People with Lynch syndrome have a mutation in one of four different genes that are responsible for fixing mistakes that occur when DNA is copied before cells divide -- so some of those errors never get repaired.
The link between mutations in the DNA-fixing genes and colon and endometrial cancers is well established. Doctors recommend that people with Lynch syndrome get colonoscopies more often than guidelines suggest for normal-risk people, and women often have their uterus removed when they're done having kids.
But for breast and pancreatic cancers especially, evidence has been mixed. And in other cancers, no clear link to Lynch syndrome has been recorded.

"We don't really know why it increases the risk of some cancers but not others," Jenkins said.
His colleague Aung Win led a team of researchers from Australia, New Zealand, Canada and the United States who followed 446 people with the gene mutations and 1,029 of their mutation-free relatives that were tested because someone in their family had colon or another cancer.

At the start of the study, none of the participants had been diagnosed with cancer themselves.
Among people with a family history of colon cancer, four percent of those with mutations were diagnosed with the disease during the next five years, compared to less than half a percent of their mutation-free relatives.

Jenkins and his colleagues calculated that over five years, people with Lynch syndrome had 20 times the normal risk of colon cancer. Their risk was also 10 times higher than usual for pancreatic cancer, and four times higher for breast cancer.

People with the mutations also seemed to be at increased risk of endometrial, ovarian, stomach, bladder and kidney cancers.

In contrast, their relatives without the mutations didn't have an increased risk of any type of cancer, compared to expected rates of new diagnoses.

LINK STILL CONTROVERSIAL
The link between Lynch syndrome and breast cancer in particular is still a controversial one, according to Dr. Albert de la Chapelle, a cancer geneticist from The Ohio State University in Columbus.

"It could be that there really is a slightly increased risk to get breast cancer," said de la Chapelle, who has worked with some of the authors before but wasn't involved in the new report.

But the conclusions, he said "are based on very small numbers," for example just 12 cases of breast cancer in mutation carriers and non-carriers combined.

Dr. Jinru Shia, from Memorial Sloan-Kettering Cancer Center in New York, told Reuters Health that the breast cancer result "goes along with our anecdotal experience" at her hospital.

The findings don't mean that everyone who tests positive for Lynch syndrome should get frequent screening for all cancers that were tied to the gene mutations, researchers agreed.

"Currently, screening is recommended for bowel cancer for people with this mutation, and we know that that screening works. For other cancers, there's less evidence that screening is effective," Jenkins said.
For example, if screening tests aren't very specific or cancers are very rare, the tests may detect more false positives -- leading to unnecessary tests and treatment -- than real cancers.

"Before we would recommend increased screening for breast cancer, for example, we'd have to have stronger evidence that the increased risk we observed was real and that (mammography) or other types of screening are effective," he said.

"GOOD NEWS FOR THESE PEOPLE"
Meanwhile, Jenkins said the results are encouraging for the family members of people with Lynch syndrome who are themselves mutation-free and "don't need to worry" about any extra cancer risk.

That's been a concern because researchers have thought other genes, besides the four Lynch syndrome mutations, could be influencing cancer risks in those families.

"Now, one can say with confidence that those who turn out not to have the mutation, that their risk is the average risk," de la Chapelle told Reuters Health.

"That is very good news for these people."

SOURCE: bit.ly/wE8Msu Journal of Clinical Oncology, online February 13, 2012.

Tuesday, February 21, 2012

Interview With An Expert -- Pancreatic Cancer Support


Need expert advice about pancreatic and what to do next.  The Lustgarten Foundation has a myriad of great resources.  Visit:



Interview With An Expert covers topics of interest to individuals with pancreatic cancer. Free copies are available by request to The Lustgarten Foundation and can be downloaded in PDF format. Bulk copies are also available to health care professionals.

  

Monday, February 20, 2012

Denver Hospice Memorial Wall Dedication


Miller3
 
Please Join Us for the Dedication
of the Louann and Micky Miller Family
Light Up A Life Memorial Wall
 
    
Where:

Date:
Time:


The Denver Hospice Inpatient Care Center
8299 E. Lowry Blvd., Denver, CO 80230
Wednesday, March 7, 2012
10:00 a.m. (followed by optional tours)
Please RSVP by Friday, March 2 to Ray Merenstein
at (303) 226-5486 or rmerenstein@denverhospice.org


Miller2

Sunday, February 19, 2012

Visit Rocky Mountain Cancer Centers' New Website

 

In December 2011, Rocky Mountain Cancer Centers (RMCC) released a new website designed to help serve up the information that is most important when looking for cancer treatment.  Patients can easily learn about physicians, treatments and locations.  Plus, they can make appointments and pay bills online.  The idea was to make the experience as easy and as human as possible.  As with everything at RMCC, as the largest cancer care provider in Colorado, their goal is to provide state of the art integrative treatment with compassion and love.  Love Heals.

http://rockymountaincancercenters.com/

Saturday, February 18, 2012

My Faith: What people talk about before they die


Editor's Note: Kerry Egan is a hospice chaplain in Massachusetts and the author of "Fumbling: A Pilgrimage Tale of Love, Grief, and Spiritual Renewal on the Camino de Santiago."

By Kerry Egan, Special to CNN

As a divinity school student, I had just started working as a student chaplain at a cancer hospital when my professor asked me about my work.  I was 26 years old and still learning what a chaplain did.
"I talk to the patients," I told him.

"You talk to patients?  And tell me, what do people who are sick and dying talk to the student chaplain about?" he asked.

I had never considered the question before.  “Well,” I responded slowly, “Mostly we talk about their families.”

“Do you talk about God?

“Umm, not usually.”

“Or their religion?”

“Not so much.”

“The meaning of their lives?”

“Sometimes.”

“And prayer?  Do you lead them in prayer?  Or ritual?”

“Well,” I hesitated.  “Sometimes.  But not usually, not really.”

I felt derision creeping into the professor's voice.  “So you just visit people and talk about their families?”

“Well, they talk.  I mostly listen.”

“Huh.”  He leaned back in his chair.

A week later, in the middle of a lecture in this professor's packed class, he started to tell a story about a student he once met who was a chaplain intern at a hospital.

“And I asked her, 'What exactly do you do as a chaplain?'  And she replied, 'Well, I talk to people about their families.'” He paused for effect. “And that was this student's understanding of  faith!  That was as deep as this person's spiritual life went!  Talking about other people's families!”

The students laughed at the shallowness of the silly student.  The professor was on a roll.

“And I thought to myself,” he continued, “that if I was ever sick in the hospital, if I was ever dying, that the last person I would ever want to see is some Harvard Divinity School student chaplain wanting to talk to me about my family.”

My body went numb with shame.  At the time I thought that maybe, if I was a better chaplain, I would know how to talk to people about big spiritual questions.  Maybe if dying people met with a good, experienced chaplain they would talk about God, I thought.

Today, 13 years later, I am a hospice chaplain.  I visit people who are dying in their homes, in hospitals, in nursing homes.   And if you were to ask me the same question - What do people who are sick and dying talk about with the chaplain?  – I, without hesitation or uncertainty, would give you the same answer. Mostly, they talk about their families: about their mothers and fathers, their sons and daughters.

They talk about the love they felt, and the love they gave.  Often they talk about love they did not receive, or the love they did not know how to offer, the love they withheld, or maybe never felt for the ones they should have loved unconditionally.

They talk about how they learned what love is, and what it is not.    And sometimes, when they are actively dying, fluid gurgling in their throats, they reach their hands out to things I cannot see and they call out to their parents:  Mama, Daddy, Mother.

What I did not understand when I was a student then, and what I would explain to that professor now, is that people talk to the chaplain about their families because that is how we talk about God.  That is how we talk about the meaning of our lives.  That is how we talk about the big spiritual questions of human existence.

We don't live our lives in our heads, in theology and theories.  We live our lives in our families:  the families we are born into, the families we create, the families we make through the people we choose as friends.
This is where we create our lives, this is where we find meaning, this is where our purpose becomes clear.
Family is where we first experience love and where we first give it.  It's probably the first place we've been hurt by someone we love, and hopefully the place we learn that love can overcome even the most painful rejection.

This crucible of love is where we start to ask those big spiritual questions, and ultimately where they end.
I have seen such expressions of love:  A husband gently washing his wife's face with a cool washcloth, cupping the back of her bald head in his hand to get to the nape of her neck, because she is too weak to lift it from the pillow. A daughter spooning pudding into the mouth of her mother, a woman who has not recognized her for years.

A wife arranging the pillow under the head of her husband's no-longer-breathing body as she helps the undertaker lift him onto the waiting stretcher.

We don't learn the meaning of our lives by discussing it.  It's not to be found in books or lecture halls or even churches or synagogues or mosques.  It's discovered through these actions of love.
If God is love, and we believe that to be true, then we learn about God when we learn about love. The first, and usually the last, classroom of love is the family.

Sometimes that love is not only imperfect, it seems to be missing entirely.  Monstrous things can happen in families.  Too often, more often than I want to believe possible, patients tell me what it feels like when the person you love beats you or rapes you.  They tell me what it feels like to know that you are utterly unwanted by your parents.  They tell me what it feels like to be the target of someone's rage.   They tell me what it feels like to know that you abandoned your children, or that your drinking destroyed your family, or that you failed to care for those who needed you.

Even in these cases, I am amazed at the strength of the human soul.  People who did not know love in their families know that they should have been loved.  They somehow know what was missing, and what they deserved as children and adults.

When the love is imperfect, or a family is destructive, something else can be learned:  forgiveness.  The spiritual work of being human is learning how to love and how to forgive.

We don’t have to use words of theology to talk about God; people who are close to death almost never do. We should learn from those who are dying that the best way to teach our children about God is by loving each other wholly and forgiving each other fully - just as each of us longs to be loved and forgiven by our mothers and fathers, sons and daughters.

The opinions expressed in this commentary are solely those of Kerry Egan.


http://religion.blogs.cnn.com/2012/01/28/my-faith-what-people-talk-about-before-they-die/

Friday, February 17, 2012

ADVANCED PANCREATIC CANCER CLINICAL TRIAL OPENS AT UNIVERSITY OF COLORADO CANCER CENTER



Combination of targeted therapy, chemotherapy, showed promise in Phase I trial

11/23/2010
 

AURORA, Colo. - The University of Colorado Cancer Center is enrolling patients in a clinical trial for a new treatment for advanced pancreatic cancer that showed promise in early clinical trials.
“Pancreatic cancer remains of the most difficult to treat,” says Wells Messersmith, MD, FACP, director of the University of Colorado Cancer Center gastrointestinal medical oncology at University of Colorado Hospital. “In fact it has the highest mortality rate of all major cancers, with only six percent of patients surviving more than five years from diagnosis. People with advanced disease live only a few months after diagnosis, and there hasn’t been much improvement in survival over the past 40 years. That’s why this new treatment is exciting.”
The new oral treatment, IPI-926 from Infinity Pharmaceuticals, Inc., takes a new approach—blocking the Hedgehog pathway. Scientists think this pathway plays a key role in passing information to adult stem cells that regulate tissue regeneration, and that if the pathway breaks down, diseases like cancer occur.
The Phase 1b/2 clinical trial is for patients with previously untreated pancreatic cancer that has spread beyond the initial tumor site (metastatic disease). Patients enrolled in the trial will be treated with a combination of IPI-926 andGemzar® (gemcitabine), a chemotherapy drug used to treat advanced pancreatic cancer.
In a Phase I study, a single daily dose of IPI-926 was well-tolerated and resulted in clinical activity in patients with basal cell carcinoma. The new trial will first aim to determine the recommended combined therapy dose for a multi-center, randomized, double-blind Phase 2 study, which will evaluate overall survival, progression-free survival, time to progression and overall response.
“Clinical trials that evaluate potential new treatments for pancreatic cancer, like this study with IPI-926, represent important efforts and potentially promising clinical advances to find more effective ways to better treat patients and make a meaningful difference in their lives,” says Messersmith, associate professor of medical oncology at the University of Colorado School of Medicine. “There are many patients in Denver, in Colorado and in the Rocky Mountain region who are waiting for an alternative, and we are hopeful that our efforts will have a positive impact.”
About 43,140 Americans will be diagnosed with pancreatic cancer this year and 36,800 will die from the disease, according to the American Cancer Society website, http://cancer.org. About 430 Coloradoans died from the disease in 2009, the website said.
Clinical Contact Information
For information about the Colorado arm of this clinical trial, please contact Stacy Grolnic, UCCC Phase I Team Coordinator, at 720-848-0655 orstacy.grolnic@ucdenver.edu.
About the University of Colorado Cancer Center
The University of Colorado Cancer Center is the Rocky Mountain region’s only National Cancer Institute-designated comprehensive cancer center. NCI has given only 40 cancer centers this designation, deeming membership as “the best of the best.” Headquartered on the University of Colorado Denver Anschutz Medical Campus, UCCC is a consortium of three state universities (Colorado State University, University of Colorado at Boulder and University of Colorado Denver) and five institutions (The Children’s Hospital, Denver Health, Denver VA Medical Center, National Jewish Health and University of Colorado Hospital). Together, our 440+ members are working to ease the cancer burden through cancer care, research, education and prevention and control. Learn more at www.uccc.info.
About Infinity Pharmaceuticals, Inc.
Infinity (NASDAQ: INFI) is an innovative drug discovery and development company seeking to discover, develop, and deliver to patients best-in-class medicines for difficult-to-treat diseases. Infinity combines proven scientific expertise with a passion for developing novel small molecule drugs that target emerging disease pathways. Infinity’s programs in the inhibition of the Hsp90 chaperone system, the Hedgehog pathway, fatty acid amide hydrolase and phosphoinositide-3-kinase are evidence of its innovative approach to drug discovery and development. For more information on Infinity, please refer to the company’s website athttp://www.infi.com.
# # #
Contact: Lynn Clark, 303-724-3160, lynn.clark@ucdenver.edu

Thursday, February 16, 2012

Do sausages cause cancer?


Eating processed meat may put you at almost as much risk of pancreatic cancer as smoking.

Did you know?

More than 2000 Australians are diagnosed with pancreatic cancer every year. There is a greater risk of dying from it than a car accident.

Consuming more than 150 grams of processed meat a day – that equates to roughly three sausages – puts you at almost as much risk of pancreatic cancer as a smoker.

A new report from Sweden has found eating more than 150 grams of processed meat lifts the risk of developing pancreatic cancer to 57 per cent. Smoking increases the risk of pancreatic cancer by up to 70 per cent.

The consumption of red meat –  and in particular processed meat – is also associated with an increased risk of bowel, oesophageal and lung cancer. Processed meat consumption has also been linked to stomach and prostate cancer.

Processed meat includes ham, bacon, sausages, salami, prosciutto and corned beef, and the study found even one sausage a day increases your pancreatic cancer risk by a fifth.


Preservative problems

Clare Hughes, Cancer Council nutrition program manager, says a number of studies have linked processed meat to cancer and the problem is multi-fold.

"Processed meats are high in salt and fat. In addition, chemicals such as nitrites are added to many processed meats to maintain their colour and to prevent contamination. Nitrites can be converted in the stomach to carcinogenic nitrosamines."

In Australia, there are national guidelines set on the type and levels of preservatives used in processed meat.

These are then passed on by Food Standards Australia New Zealand (FSANZ) to the various states and territories. However, according to an FSANZ spokesperson, the monitoring of these practices is up to each state, some of which do so very assiduously and some less so.


How much is too much?How much is too much?

So is there a safe amount of processed meat we can eat?

"Eating 50 grams once a week is probably okay. Eat it daily and you're setting yourself up for trouble," says Dr Alan Barclay, a spokesman for the Dietitians Association of Australia.

"A similar study conducted last year found a link between red and processed meats and an 18 per cent increased risk of colorectal cancer, so there is some very strong evidence." Barclay says fruit and vegies have protective factors against cancer and suggests adding lots of salad to your ham sandwich, or eating good-quality sausages with lots of vegies.

However, the best option may be to avoid these foods altogether, Barclay says.

"Cook a roast and slice up the leftovers for sandwiches. You don't have to buy cured processed meats. You're just better off not risking it."

Pancreatic cancer is one of the most lethal forms of cancer, with less than five per cent of patients living beyond five years.


What is 50 grams of processed meat?

  • One sausage
  • Two medium slices of ham
  • One hotdog or frankfurter
  • Two medium rashers of bacon
  • A 1cm thick slice of salami
  • Two slices of luncheon meat
Read our fact sheet on pancreatic cancer.

Wednesday, February 15, 2012

Goodbye to two greats : Ben Gazzara and Zalman King


Author : "Caffeinated" Clint (Saturday, February 4th, 2012 at 1:54 am)



Two of cinema’s most proficient, actor Ben Gazzara and filmmaker/writer Zalman King have left us for the multiplex in the sky.

Gazzara, 81, probably best known to readers as the villain in Swayze ‘gem’ “Roadhouse” (1989), succumbed to Pancreatic cancer. His many other film and television credits include “Anatomy of a Murder”, “The Strange One”, “Run for Your Life” and “The Big Lebowski”.

Bloody great actor. Big-ass loss.

Zalman King, 69, is a name most of our readers will recognize; he was the man who gave us our jollies throughout the ’80s and early ’90s with such soft-porn classics as “Nine and a Half Weeks” (he co-wrote the pic), “Two Moon Junction”, and TV’s “Red Shoe Diaries”. Some might also remember that King was an actor before he started concealing himself behind the lens, starring in films like “Galaxy of Terror”.

Though “Two Moon Junction” was obviously the high-point of King’s directing career, it’s “Wild Orchid” that probably received the most publicity. Aside from causing quite a ruckus and garnering lots of attention when it was screening at the Drive-In I worked at as a youngster (it’s rumoured barrage of 18+ sex scenes led to many asking if I could sneak them in), the movie got lots of attention because of how real Mickey Rourke and Carre Otis’s sex scenes were – it was said that they weren’t actually pretending to screw onscreen. That was the real thing. The movie was atrocious, but it certainly gained a reputation and quickly.

Both Gazzara and King, specifically for their work in “Roadhouse” and “Two Moon Junction”, respectively, played a big part in my cinematic diet back in the ’80s. Thanks for all your fun, hot, tight nights gentlemen.