NCI Cancer Center News
Duke study elucidates why stress causes DNA damage:
For years, researchers have published papers that associate chronic stress with chromosomal damage. Now researchers at Duke University Medical Center have discovered a mechanism that helps to explain the stress response in terms of DNA damage... In the study, mice were infused with an adrenaline-like compound that works through a receptor called the beta adrenergic receptor... The scientists found that this model of chronic stress triggered certain biological pathways that ultimately resulted in accumulation of DNA damage.
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Among the research institutions NCI funds across the United States, it currently designates 66 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.
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